BPC-157
Also known as: Body Protection Compound-157, PL 14736, Bepecin
4.7
out of 5.0
A pentadecapeptide derived from human gastric juice with broad tissue-healing properties, extensively studied for tendon, ligament, muscle, and gut repair.
Research Overview
The peptide's mechanism of action involves multiple pathways including upregulation of growth factor expression (VEGF, EGF, and others), promotion of angiogenesis, modulation of the nitric oxide system, and interaction with the dopaminergic system. BPC-157 has demonstrated the ability to accelerate healing in tendons, ligaments, muscles, bones, and the gastrointestinal tract in animal studies. Its gastric origin gives it notable stability in stomach acid, allowing for both oral and injectable administration.
Preclinical research has shown BPC-157's efficacy in healing Achilles tendon transections, muscle crush injuries, colonic anastomoses, and various forms of GI damage including NSAID-induced lesions. It has also demonstrated neuroprotective properties, including counteracting the effects of dopaminergic neurotoxins. While human clinical trial data remains limited, the breadth and consistency of animal research results have made BPC-157 one of the most widely discussed healing peptides.
Documented Research Effects
Dosage & Protocol
Typical Dose Range
250 – 500
mcg per dose
Frequency
1-2x daily
Cycle Length
4-12 weeks
Common Vial Sizes
Calculate exact draw volumes and reconstitution steps.
Use CalculatorDosage information is for research reference only. Always follow established research protocols. Not medical advice.
Storage & Handling
Lyophilized Powder
Reconstituted Solution
Frequently Asked Questions
The most commonly researched dosage of BPC-157 is 250-500 mcg per day, administered via subcutaneous injection. Many protocols split this into two doses (e.g., 250 mcg morning and 250 mcg evening). Dosage should be tailored to body weight and the severity of the injury being addressed.
Add 2 mL of bacteriostatic water (BAC water) slowly down the side of the vial, allowing it to dissolve naturally without shaking. For a 5 mg vial reconstituted with 2 mL of BAC water, each 0.1 mL (10 units on an insulin syringe) equals 250 mcg. Store the reconstituted solution refrigerated at 2-8 degrees Celsius.
Yes, BPC-157 has demonstrated stability in gastric acid and has shown efficacy via oral administration in research studies, particularly for gastrointestinal conditions such as inflammatory bowel disease and ulcers. However, subcutaneous injection near the injury site is generally considered more effective for musculoskeletal injuries.
BPC-157 is typically injected subcutaneously (into the fat layer under the skin). For localized injuries, injecting as close to the injury site as possible is recommended. Common injection sites include the abdomen, thigh, or the area surrounding the injury. Rotate injection sites to prevent tissue irritation.
Many users report noticeable improvement within the first 1-2 weeks of use, with more significant healing observed over 4-8 weeks. The timeline depends on the type and severity of the injury. Tendon and ligament injuries typically require longer protocols (8-12 weeks) compared to muscle injuries (4-6 weeks).
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