MOTS-c
Also known as: Mitochondrial ORF of the Twelve S rRNA type-c
A 16-amino-acid mitochondrial-derived peptide that activates AMPK, regulates metabolic homeostasis, and enhances insulin sensitivity and exercise capacity.
Category
Peptides targeting mitochondrial function, cellular senescence, and fundamental aging pathways. These compounds aim to improve cellular energy production, clear senescent cells, and support metabolic homeostasis at the mitochondrial level.
5 peptides in this category
Also known as: Mitochondrial ORF of the Twelve S rRNA type-c
A 16-amino-acid mitochondrial-derived peptide that activates AMPK, regulates metabolic homeostasis, and enhances insulin sensitivity and exercise capacity.
Also known as: HN, HNG (S14G-Humanin)
A 24-amino-acid mitochondrial-derived peptide with cytoprotective properties, researched for protection against oxidative stress, neurodegeneration, and age-related cellular damage.
Also known as: Elamipretide, MTP-131, Bendavia
A synthetic mitochondria-targeted tetrapeptide that stabilizes cardiolipin in the inner mitochondrial membrane, improving energy production and reducing oxidative stress.
Also known as: 5-Amino-1-methylquinolinium
A small-molecule NNMT inhibitor that increases intracellular NAD+ levels and suppresses fat cell formation, researched for metabolic regulation and fat loss.
Also known as: Proxofim, FOXO4-D-Retro-Inverso
A 49-amino-acid senolytic peptide that selectively induces apoptosis of senescent cells by disrupting the FOXO4-p53 interaction, restoring tissue function in aged organisms.